First slide

Inheritance of One Gene

Question

The pleiotropic disease phenylketonuria, which occurs in humans is caused by a single mutation in the gene that codes for the enzyme.

Easy

A

Tyrosinase
B

Phenyl pyruvate kinase
C

Phenyl alanine hydroxylase
D

Carboxy dismutase

Solution

Phenylketonuria is caused by a single gene mutation in the gene which codes for phenylalanine hydroxylase. This manifests itself through phenotypic expression characterized by mental retardation and a reduction in hair and skin pigmentation.

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