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Q.

Select the correct statement about about RNAi process.(a) It involves silencing of a specific mRNA(b) A cellular mechanism that uses the genes' own DNA sequence to turn off mRNA expression.(c) It is a type of cellular defense.

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a

a only

b

a and b only

c

b and c only

d

a, b and c

answer is D.

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Detailed Solution

RNAi takes place in all eukaryotic organisms as a method of cellular defense. This method involves silencing of a specific mRNA due to a complementary dsRNA molecule that binds to and prevents translation of the mRNA (silencing). The source of this complementary RNA could be from an infection by viruses having RNA genomes or mobile genetic elements (transposons) that replicate via an RNA intermediate.
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