Select the correct statement regarding Okazaki fragments formed during DNA replication.
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a
They are the short DNA fragments on the lagging strand.
b
They are the short DNA fragments on the leading strand.
c
They are the RNA primes required for initiation of DNA synthesis.
d
They are the fragments of DNA produced by DNase.
answer is A.
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Detailed Solution
The formation of new chain always takes place in 5' - 3' direction. As a result of this, one chain of DNA is continuously formed and it is termed as Leading strand. The formation of second chain begins from the centre and not from the terminal points, so this chain is discontinuous and is made up of small segments called Okazaki Fragments. This discontinuous chain is termed as Lagging strand. Ultimately all these segments joined together and a complete new chain is formed.