First slide

Translation

Question

The small subunit of ribosome select the initial AUG codon of mRNA to be placed at its P site as opposed to some internal one in bacterial ribosome because of

Easy

A

presence of cap at the 5â of mRNA
B

presence of methylated A in the initiation codon
C

presence of TATA box
D

presence of ShineâDalgarno sequence a head of start codon.

Solution

Bacterial mRNAs possess a specific sequence of nucleotides (called the ShineâDalgarno sequence after its discoverers) that resides five to 10 nucleotides before the initiation codon. The ShineâDalgarno sequence is complementary to a sequence of nucleotides near the 3 â² end of the 16S ribosomal RNA of the small ribosomal subunit.

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