Under which of the following conditions there will be no change in the reading frame of following mRNA?
5' AACAGCGGUGCUAUU 3'
Genetic code is triplet.If we delete GGU from 7th , 8th and 9th position then the entire codon will be deleted. Hence there will not be any change in the reading frame.
Insertion of a single nucleotide alter the reading frame and will lead to frame shift mutation
Deletion of a single nucleotide alter the reading frame and will lead to frame shift mutation.
Addition of A and G will also alter the reading framing as genetic code is triplet.