When cell has stalled DNA replication fork, which checkpoint should be predominantly activated?
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a
G1/S
b
G2/M
c
M
d
Both G2/M and M
answer is A.
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Detailed Solution
If cell has stalled DNA replication fork, then G1/S genetic check point should be predominantly activated otherwise replication fork can’t established (stalled). Even after replication fork formation cell cycle can be stop at G2/M checkpoint if DNA replication occur abnormal or erroneous. Formation of replication fork is not an assurance of cell division. But without activation of G1/S check point cell can’t initiate replication fork.