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Q.

When cell has stalled DNA replication fork, which checkpoint should be predominantly activated?

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a

G1/S

b

G2/M

c

M

d

Both G2/M and M

answer is A.

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Detailed Solution

If cell has stalled DNA replication fork, then G1/S genetic check point should be predominantly activated otherwise replication fork can’t established (stalled). Even after replication fork formation cell cycle can be stop at G2/M checkpoint if DNA replication occur abnormal or erroneous. Formation of replication fork is not an assurance of cell division. But without activation of G1/S check point cell can’t initiate replication fork.
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