First slide

Nature of Bond Linking Monomers in a Polymer

Question

Which of the following biomolecules does have a phosphodiester bond?

Easy

A

Amino acids in a polypeptide
B

Nucleic acids in a nucleotide
C

Fatty acids in a diglyceride
D

Monosaccharides in a polysaccharide

Solution

Phosphodiester bond is present between the nucleotides in a nucleic acid.
In a nucleic acid a phosphate moiety links the 3’-carbon of one sugar of one nucleotide to the 5’-carbon of the sugar of the succeeding nucleotide. The bond between the phosphate and hydroxyl group of sugar is an ester bond. As there is one such ester bond on either side, it is called phosphodiester bond.

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