First slide

RNA World

Question

Which of the following feature makes the RNA chemically more reactive and structurally less stable nucleic acid than DNA?

Easy

A

Less rate of mutation.
B

Indirect involvement in protein synthesis.
C

Free 2’ H group.
D

Catalytic nature.

Solution

RNA used to act as a genetic material as well as a catalyst (there are some important biochemical reactions in living systems that are catalysed by RNA catalysts and not by protein enzymes). But, RNA being a catalyst was reactive and hence unstable. Therefore, DNA has evolved from RNA with chemical modifications that make it more stable.

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