First slide

Eukaryotic Cells

Question

Which of the following sequences represent a possible pathway in the production of a secretory protein?

Easy

A

Rough ER → Secretory vesicle → Ribosome → Golgi apparatus
B

Ribosome → Rough ER → Golgi apparatus → Secretory vesicle
C

Secretory vesicle → Golgi apparatus → Ribosomes → Rough ER
D

Rough ER → Ribosomes → Secretory vesicles → Golgi apparatus

Solution

The golgi apparatus principally performs the function of packaging materials, to be delivered either to the intra-cellular targets or secreted outside the cell. Materials to be packaged in the form of vesicles from the ER fuse with the cis face of the golgi apparatus and move towards the maturing face. A number of proteins synthesised by ribosomes on the endoplasmic reticulum are modified in the cisternae of the golgi apparatus before they are released from its trans face.
Therefore, the best sequence to represent a possible pathway in the production of secretory protein is:
Ribosome $\to$ Rough ER $\to$ Golgi apparatus $\to$ Secretory vesicles

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