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Questions  

Which of the following statements is correct?

a
Francis Crick proposed the Reverse Central dogma in molecular biology.
b
The pitch of the helix is 3.4 mm
c
The ratios between Adenine and Thymine, and Guanine and Cytosine varies from one organism to another.
d
Two nucleotides are linked through 3'-5' phosphodiester linkage to form a dinucleotide.

detailed solution

Correct option is D

When a phosphate group is linked to OH of 5' C of a nucleoside through phosphoester linkage, a corresponding nucleotide (or deoxynucleotide depending upon the type of sugar present) is formed. Two nucleotides are linked through 3'-5' phosphodiester linkage to form a dinucleotide. Two nucleotides are linked through 3'-5' phosphodiester linkage to form a dinucleotide. Francis Crick proposed the Central dogma in molecular biology.The pitch of the helix is 3.4 nm.The ratios between Adenine and Thymine, and Guanine and Cytosine are constant and equals one.

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