First slide

The DNA

Question

Which of the following statements is correct ?

Easy

A

Adenine pairs with thymine through one H-bond.
B

Adenine pairs with thymine through three H-bonds.
C

Adenine does not pair with thymine.
D

Adenine pairs with thymine through two H-bonds.

Solution

In a ds DNA adenine pair with thymine through 2H bonds while cytosine pairs with guanine through 3H bonds and vice-versa. As a result, always a purine comes opposite to a pyrimidine. This generates approximately uniform distance between the two strands of the helix

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