Which of the following statements is correct in relation to the endocrine system?

Non-nutrient chemicals produced by the body in trace amoun ts that act as intercellular messenger are known as hormones.

Releasing and inh ibitory hormones are  produced  by the pituitary gland.

Adenoh ypophysis is under direct neural regulation of the hypothalamus.

Organ s in the body like gastrointestinal tract, heart, kidney and liver do not produce any hormones.