Questions
Which of the following statements regarding enzyme inhibition is correct ?
detailed solution
Correct option is B
Competitive inhibition is seen when the substrate and the inhibitor compete.These inhibitiors resemble the structure of substrate and are also called as “substrate analogues”. Competitive inhibitors bind to active site of enzyme there by decreasing the probability of binding substrate molecule to enzyme.Noncompetitive inhibition of an enzyme cannot be overcome by adding large amount of substrate.Inhibitors which do not resemble the substrate in structure but decrease the activity of the enzyme are called noncompetitive inhibitors, and this process is called noncompetitive inhibition. They bind to the enzyme at any place other than active site and renders it inactive. The shape of the active site is changed. Hence the substrate molecule cannot occupy the active site.Non-competitive inhibitors often bind to the enzyme reversibly or irreversibly.Talk to our academic expert!
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