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Q.

The most important contribution to the stability of a protein conformation appears to be the

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a

entropy increase from the decrease in ordered water molecules forming a solvent shell around it

b

maximum entropy increase from ionic interactions between the ionized amino acids in a protein

c

sum of free energies of formation of many weak interactions between its polar amino acids and surrounding water molecules

d

sum of free energies of formation of many weak interactions among the hundreds of amino acids in a protein

answer is D.

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Detailed Solution

Several weak electrostatic attraction exist between the amino acid units of protein. These interactions lower the free energy to a very great extent.
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The most important contribution to the stability of a protein conformation appears to be the