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Q.

Peptides are formed by the joining of amino acids through amide linkage. Which of the following statement is not true in this respect?

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a

Amide groups do not contribute in the hydrogen bonding interactions

b

pπ resonance stabilizes the amide linkages

c

Amide groups are more resistant to hydrolysis than the similar ester groups

d

Stable conformations of peptides are restricted to those having planar amide groups

answer is A.

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Detailed Solution

Hydrogen bonding plays an important role in the secondary structure of proteins. These are formed between amide groups of two chains.
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