A physician wishes to prepare a buffer solution at pH = 3. 58 that efficiently resists a change in pH yet contains only small conc. of the buffering agents. Which one of the following weak acid together with its sodium salt would be best to use?
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a
m-chloro benzoic acid (pKa = 3.98)
b
p - chlorocinnamic acid (pKa = 4.41)
c
2.5 - dihydroxy benzoic acid (pKa = 2.97)
d
Acetoacetic acid (pKa = 3.58)
answer is D.
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Detailed Solution
Given that the buffer solution contains only small concentraiton of buffering agents