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Q.

Which among the following is most acidic?

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a

b

c

d

F-CH2-CH2-CH2-CH2-COOH

answer is `.

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Detailed Solution

Because the inductive effect of fluorine decreases with distance, (a) will be most acidic, because the carboxylate ion that results after the loss of H+ can be stabilized by electron withdrawing nature of fluorine (-I effect), which is strongest in A where fluorine atom is at cr carbon.
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Which among the following is most acidic?