Which compound will be most reactive for Perkin condensation with ethanoic anhydride?
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a
b
c
d
answer is A.
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Detailed Solution
NO2 is electron with drawing and increase the positive charge on carbonyl carbon. The reaction involves nucleophilic attack in the first step is RDS in the reaction. Hence the carbon must be maximum electrophilic in nature. This is brought by minus Inductive groups.