Q.
Which of the following is considered as an anticancer species?
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a
b
c
d
answer is A.
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Detailed Solution
cis isomer of PtNH32Cl2 is used as an anticancer drugs for treating several type of malignant tumours. When it is injected into the bloodstream the more reactive Cl groups are lost so the Pt atom bonds to a N atom in guanosine (a part of DNA). This molecule can bond to two different guanosine units and by bridging between them it upsets the normal reproduction of DNA.
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