Which of the following statements is/are true?

Moderate

A

Primary and secondary amines react with acid chlorides, anhydrides and esters by nucleophilic substitution reaction.
B

In the acylation reaction of amines there is replacement of hydrogen atom of NH₂ or NH group by the acyl group
C

The products obtained in acylation reaction of amines are amides
D

All of the above

Solution

Aliphatic and aromatic primary and secondary amines react with acid chlorides, anhydrides and esters by nucleophilic substitution reaction, which is known as acylation. In this type of reaction, there is the replacement of hydrogen atom of NH₂ or NH group by acyl group. The product obtained in acylation reaction of amine is known as amide.

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