Questions
ADA deficiency leads to decrease in the number of
detailed solution
Correct option is B
ADA deficiency results in decrease in the number of lymphocytes.The function of the adenosine deaminase enzyme is to eliminate a molecule called deoxyadenosine, which is generated when DNA is broken down. Adenosine deaminase converts deoxyadenosine, which can be toxic to lymphocytes, to another molecule called deoxyinosine that is not harmful. Mutations in the ADA gene reduce or eliminate the activity of adenosine deaminase and allow the buildup of deoxyadenosine to levels that are toxic to lymphocytes.Similar Questions
Select the true statements from the following regarding insulin.
(a) Insulin from animal source, may develop allergy in some patients.
(b) Recombinant insulin does not induce unwanted immunological responses.
(c) Chain A and chain B are linked together by disulphide bridges.
(d) C-peptide is absent in proinsulin.
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