First slide

Mechanism of Hormone Action

Question

The amino acid tryptophan is the precursor for the synthesis of

Moderate

A

estrogen and progesterone
B

cortisol and cortisone
C

melatonin and serotonin
D

thyroxine and triiodothyronine.

Solution

The precursor to melatonin is serotonin, a neurotransmitter that itself is derived from the amino acid tryptophan. Within the pineal gland, serotonin is acetylated and then methylated to yield melatonin. The synthesis and secretion of melatonin are dramatically affected by light exposure to the eyes.

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