Choose the correct statement/s regarding malaria(i) Malignant malaria is caused by Plasmodium vivax.(ii) Frequent chills and fever are caused by hemozoin.(iii) Sporozoites reproduce sexually in hepatocytes.(iv) Gametocytes develop in RBCs.

The rupture of RBCs is associated with release of a toxic substance, haemozoin, which is responsible for the chill and high fever recurring every three to four days.Gametocytes develop in human RBCs and undergo fertilisation in the crop of mosquito.Malignant malaria is caused by Plasmodium falciparum.Sporozoites reproduce asexually in hepatocytes.