First slide

Transport of Gases

Question

Compared to arterial blood, the plasma of venous blood has

Moderate

A

a higher concentration of HCO₃^– and a lower concentration of Cl^–
B

a higher concentration of HCO₃^– as well as Cl^–
C

a lower concentration of HCO₃^– and a higher concentration of Cl^–
D

a lower concentration of HCO₃^– as well as Cl^–

Solution

Venous blood plasma has both a higher concentration of bicarbonate and a lower concentration of chloride due to chloride shift.
Due to the activity of carbonic anhydrase enzyme, the concentration of HCO₃^– increases inside RBCs of venous blood at the tissues. Some HCO₃^– moves out into the blood plasma, down its concentration gradient. In exchange, Cl^–move from plasma into the RBCs. The net effect of chloride shift is that CO₂ is removed from tissue cells and is transported in blood plasma as HCO₃^–.

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