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Q.

Due to non-disjunction of chromosomes during spermatogenesis, some sperms carry both sex chromosomes (22A+XY) and some sperms  do not carry any sex chromosome (22A+0). If these sperms fertilise normal eggs (22A+X) which type of genetic disorders appear among off springs?

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a

Down’s syndrome and Edward syndrome

b

Klinefelter’s syndrome and Turner’s syndrome

c

Down’s syndrome and Turner’s syndrome

d

Klinefelter’s syndrome and Down’s syndrome

answer is B.

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Detailed Solution

If sperm of with no sex chromosomes fertilises an ovum with X chromosome, it results in zygote with XO (Turner's syndrome).If sperm with XY chromosomes fertilises an ovum with X chromosomes, it results in zygote with XXY (Klinefelter's Syndrome).Edward Syndrome - Trisomy 18Down's Syndrome - Trisomy 21
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