First slide

Biotechnological Applications in Medicine

Question

In gene therapy to treat adenosine deaminase deficiency disorder, which of the patients blood cells are used ?

Easy

A

Erythrocytes
B

Lymphocytes
C

Both Erythrocytes and Lymphocytes
D

Thrombocytes

Solution

As a first step towards gene therapy, lymphocytes from the blood of the patient are grown in a culture outside the body. A functional ADA cDNA (using a retroviral vector) is then introduced into these lymphocytes, which are subsequently returned to the patient

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