Glucose homeostasis in man is maintained by

Glucagon and insulin regulate the level of blood glucose in man. Both the hormones are secreted from alpha and beta cells of pancreas respectively. Glucagon is secreted when the blood glucose levels are low and it stimulates glycogen breakdown and glucose synthesis in the liver by increasing blood glucose concentration. Rising levels of blood glucose stimulates insulin secretion, which decreases blood glucose by stimulating glycogenesis in the liver and adipocytes. Thus, insulin and glucagon maintain glucose homeostasis in blood.