Q.
The immediate effect of fall in glomerular filtration rate (GFR) is that it activates
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a
adrenal medulla to release adrenaline
b
posterior pituitary to release vasopressin
c
juxta glomerular cells to release renin
d
adrenal cortex to release aldosterone
answer is C.
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Detailed Solution
A fall in glomerular blood flow/glomerular blood pressure/GFR can activate the JG cells to release renin.Renin converts angiotensinogen in blood to angiotensin I and further to angiotensin II. Angiotensin II, being a powerful vasoconstrictor, increases the glomerular blood pressure and thereby GFR. Angiotensin II also activates the adrenal cortex to release Aldosterone. Aldosterone causes reabsorption of Na+ and water from the distal parts of the tubule. This also leads to an increase in blood pressure and GFR. This complex mechanism is generally known as the Renin-Angiotensin mechanism.
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