Q.

The immediate effect of fall in glomerular filtration rate (GFR) is that it activates

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a

adrenal medulla to release adrenaline

b

posterior pituitary to release vasopressin

c

juxta glomerular cells to release renin

d

adrenal cortex to release aldosterone

answer is C.

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Detailed Solution

A fall in glomerular blood flow/glomerular blood pressure/GFR can activate the JG cells to release renin.Renin converts angiotensinogen in blood to angiotensin I and further to angiotensin II. Angiotensin II, being a powerful vasoconstrictor, increases the glomerular blood pressure and thereby GFR. Angiotensin II also activates the adrenal cortex to release Aldosterone. Aldosterone causes reabsorption of Na+ and water from the distal parts of the tubule. This also leads to an increase in blood pressure and GFR. This complex mechanism is generally known as the Renin-Angiotensin mechanism.
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