First slide

Blood

Question

Mark the wrong statement about thrombin.

Moderate

A

Clotting factors trigger reactions leading to the formation of thrombin.
B

Thrombin is formed from the prothrombin.
C

Thrombin converts insoluble fibrinogen to soluble fibrins.
D

Concentration of thrombin increases by a positive feedback mechanism.

Solution

Thrombin converts soluble fibrinogen to insoluble fibrins. Thrombin also activates a factor that catalyzes the formation of more thrombin, driving clotting to completion through positive feedback.

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