First slide

Biotechnological Applications in Medicine

Question

Maturation of proinsulin to insulin involves

Easy

A

formation of peptide bonds
B

formation of disulphide bonds
C

cleavage of peptide bonds
D

cleavage of disulphide bonds

Solution

In humans, proinsulin consists of 86 amino acids (21 acids of A chain, 30 amino acids of B chain, the C peptide connecting the two has 35 amino acids). During maturation of proinsulin loses C peptide to form insulin. Hence, the peptide bonds are cleaved.
Mature insulin has A chain (21 amino acids) and B chain (30 amino acids) bound by disulphide bonds.

Get Instant Solutions

When in doubt download our app. Now available Google Play Store- Doubts App

Recieve an sms with download link

Doubts App

OR

SCAN ME

Doubts App

Doubts App