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Q.

In the ovary of female human, degeneration of a large number of primary follicles occurs during which phase?

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a

From menarch to menopause

b

From birth to puberty

c

From foetal stage to birth

d

From menopause to death

answer is B.

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Detailed Solution

Oogenesis is initiated during the embryonic development stage when a couple of million gamete mother cells (oogonia) are formed within each fetal ovary; no more oogonia are formed and added after birth. These cells start division and enter into prophase-I of the meiotic division and get temporarily arrested at that stage, called primary oocytes. Each primary oocyte then gets surrounded by a layer of granulosa cells and is called the primary follicle. A large number of these follicles degenerate during the phase from birth to puberty. Therefore, at puberty only 60,000-80,000 primary follicles are left in each ovary.
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