In the ovary of female human, degeneration of a large number of primary follicles occurs during which phase?
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a
From menarch to menopause
b
From birth to puberty
c
From foetal stage to birth
d
From menopause to death
answer is B.
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Detailed Solution
Oogenesis is initiated during the embryonic development stage when a couple of million gamete mother cells (oogonia) are formed within each fetal ovary; no more oogonia are formed and added after birth. These cells start division and enter into prophase-I of the meiotic division and get temporarily arrested at that stage, called primary oocytes. Each primary oocyte then gets surrounded by a layer of granulosa cells and is called the primary follicle. A large number of these follicles degenerate during the phase from birth to puberty. Therefore, at puberty only 60,000-80,000 primary follicles are left in each ovary.