First slide

Human Endocrine System

Question

The secretion of parathormone is regulated mainly by the

Easy

A

Pituitary gland
B

Blood ${Ca}^{2 +}$ levels
C

Thyroid gland
D

Blood glucose levels

Solution

The secretion of PTH is regulated by the circulating levels of calcium ions. Low level of ${Ca}^{2 +}$ in the blood stimulates the parathyroid glands to release more PTH. PTH increases blood ${Ca}^{2 +}$ levels (e.g., by increasing the activity of osteoclasts). A higher-than-normal level of calcium ions ${Ca}^{2 +}$ in the blood stimulates parafollicular cells of the thyroid gland to release more calcitonin which inhibits the activity of osteoclasts, thereby decreasing the blood ${Ca}^{2 +}$ level.

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