First slide

Genetic Disorders

Question

Select the incorrect statement with regard to haemophilia.

Moderate

A

It is a dominant disease.
B

A single protein involved in the clotting of blood is affected
C

It is a sex-linked disease.
D

It is a recessive disease.

Solution

Haemophilia is a X-linked recessive trait which shows transmission from carrier female to male progeny. Single protein is affected in this condition. The three main forms of hemophilia include the following:
Hemophilia A: Caused by a lack of the blood clotting factor VIII; approximately 85% of hemophiliacs have type A disease.
Hemophilia B: Caused by a deficiency of factor IX.
Hemophilia C: Some doctors use this term to refer to a lack of clotting factor XI.

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