In sickle-cell anaemia, the shape of RCBs under oxygen tension becomes
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a
biconcave disc like
b
elongated and curved
c
circular
d
spherical
answer is B.
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Detailed Solution
The mutant haemoglobin molecule (in sickle cell anaemia) undergoes polymerisation under low oxygen tension causing the change in the shape of the RBC from biconcave disc to elongated sickle like structure.