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a
The least toxic nitrogenous waste
b
Less toxic than uric acid
c
The principal nitrogenous waste in aquatic amphibians
d
Synthesised from ammonia in the liver
answer is D.
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Detailed Solution
In ureotelic vertebrates, ammonia produced by metabolism is converted into urea in the liver through the ornithine cycle. Urea is less toxic than ammonia but more toxic than uric acid. The principal nitrogenous waste in aquatic amphibians is ammonia.