What will happen if the secretion of parietal cells of gastric glands is blocked with an inhibitor?

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Gastric juice will be deficient in chymosin.

Gastric juice will be deficient in pepsinogen.

In the absence of HCl secretion, inactive pepsinogen is not converted into the active enzyme pepsin.

Enterokinase will not be released from the duodenal mucosa and so trypsinogen is not converted to trypsin.

answer is C.

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Detailed Solution

Parietal or oxyntic cells which secrete HCl and intrinsic factor. The proenzyme pepsinogen, on exposure to hydrochloric acid gets converted into the active enzyme pepsin, the proteolytic enzyme of the stomach. So the activation of pepsinogen is affected in the absence of the HCl.

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