First slide

Blood

Question

Which of the following conditions cause erythroblastosis foetalis?

Easy

A

Both mother and foetus ${Rh}^{+ ve}$
B

Mother ${Rh}^{+ ve}$ and foetus ${Rh}^{- ve}$
C

Mother ${Rh}^{- ve}$ and foetus ${Rh}^{+ ve}$
D

Both mother and foetus ${Rh}^{- ve}$

Solution

Erythroblastosis foetalis occurs only when foetus is ${Rh}^{+ ve}$ and mother is ${Rh}^{- ve}$ . During first delivery, if ${Rh}^{+ ve}$ foetal blood mixes with mother's blood, antibodies are produced in mother's body against Rh antigen. These antibodies in successive pregnancies cross placental barrier and reach foetus, causing clumping of RBCs in foetus.

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