Which of the following conditions will stimulate parathyroid gland to release parathyroid hormone?

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Fall in active Vitamin D levels

Fall in blood Ca2+ levels

Fall in bone Ca2+ levels

Rise in blood Ca2+ levels

answer is B.

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Detailed Solution

Parathyroid hormone is a hypercalcemic hormone. It increases blood Ca2+ levels by stimulating osteoclasts. These cells cause bone resorption. The secretion of parathyroid hormone is regulated by blood calcium level. A fall in blood Ca2+levels stimulate the release of parathyroid hormone leading to release Ca2+into the blood in order to maintain calcium homeostasis. A rise in Ca2+ in blood stimulates the release of thyrocalcitonin which decreases the number and activity of osteoclasts and thereby reducing the Ca2+ levels in the blood.

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