First slide

Human Endocrine System

Question

Which of the following conditions will stimulate parathyroid gland to release parathyroid hormone?

Easy

A

Fall in active Vitamin D levels
B

Fall in blood ${Ca}^{2 +}$ levels
C

Fall in bone ${Ca}^{2 +}$ levels
D

Rise in blood ${Ca}^{2 +}$ levels

Solution

Parathyroid hormone is a hypercalcemic hormone. It increases blood ${Ca}^{2 +}$ levels by stimulating osteoclasts. These cells cause bone resorption. The secretion of parathyroid hormone is regulated by blood calcium level. A fall in blood ${Ca}^{2 +}$ levels stimulate the release of parathyroid hormone leading to release ${Ca}^{2 +}$ into the blood in order to maintain calcium homeostasis. A rise in ${Ca}^{2 +}$ in blood stimulates the release of thyrocalcitonin which decreases the number and activity of osteoclasts and thereby reducing the ${Ca}^{2 +}$ levels in the blood.

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