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Disorders of Muscular and Skeletal System
Question

Which of the following diseases is an autoimmune disorder?

Easy
Solution

Autoimmune disorders occur when the immune system attacks self-antigens. Myasthenia gravis is an autoimmune disorder affecting neuromuscular junction leading to fatigue, weakening and paralysis of skeletal muscle. The self-antibodies bind to ACh receptors at the NMJ due to which acetylcholine released from the motor neurons cannot cause muscle contraction.

Arthritis is inflammation of joints.

Osteoporosis is a age-related disorder caused due to deficiency of oestrogen.

Gout is caused due to accumulation of uric acid crystals in the joints.

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