Which of the following statements are correct?1. PCR is now routinely used to detect HIV in suspected AIDS patients.2. A single-stranded DNA or RNA tagged with a radioactive molecule (probe) is allowed to hybridize to its complementary DNA in a clone of cells followed by detection using autoradiography.3. ELISA is based on the principle of antigen-antibody interaction.4. Today transgenic models exist for many human diseases such as cancer, cystic fibrosis, rheumatoid arthritis, and Alzheimer’s.
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a
1 and 3
b
2 and 4
c
1, 3 and 4
d
1, 2, 3 and 4
answer is D.
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Detailed Solution
All the statements are correct.A single stranded DNA or RNA, tagged with a radioactive molecule (probe) is allowed to hybridise to its complementary DNA in a clone of cells followed by detection using autoradiography.Transgenic models exist for many human diseases such as cancer, cystic fibrosis, rheumatoid arthritis and Alzheimer’s.PCR is now routinely used to detect HIV in suspected AIDS patients.ELISA is based on the principle of antigen-antibody interaction.