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Which one of the following is true for mature insulin ?

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Chain B and C are linked together by disulphide bridges.
Chain A and C are linked together by peptide bonds.
C peptide is not present in it.
The number of disulphide bridges in a mature insulin are 4.

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detailed solution

Correct option is C

In mature insulin “C” peptide is not present. A chain and B chain are bound by disulphide bridges. Number of disulphide bridges are 3 (1 intra and 2 inter).

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Select the true statements from the following regarding insulin.      

(a) Insulin from animal source, may develop allergy in some patients.

(b) Recombinant insulin does not induce unwanted immunological responses.

(c) Chain A and chain B are linked together by disulphide bridges.

(d) C-peptide is absent in proinsulin.

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