At which stage of HIV infection does one usually show symptoms of AIDS?
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a
Within 15 days of sexual contact with an infected person
b
When the infected retrovirus enters host cells
c
When HIV damages large number of helper T - Lymphocytes
d
When the viral DNA is produced by reverse transcriptase
answer is C.
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Detailed Solution
The symptoms are observed in the AIDs patients, when there is drastic fall in number of T lymphocytes.In HIV replication, the progeny viruses released in the blood attack other helper T-lymphocytes. This is repeated leading to a progressive decrease in the number of helper T lymphocytes in the body of the infected person. During this period, the person suffers from bouts of fever, diarrhoea and weight loss. Due to decrease in the number of helper T lymphocytes, the person starts suffering from infections that could have been otherwise overcome such as those due to bacteria especially Mycobacterium, viruses, fungi and even parasites like Toxoplasma.