MCQs on CBSE Class 12 Biology Chapter 3 Human Reproduction

CBSE Class 12 MCQs of Biology Chapter 3: Human reproduction is one of the most important chapters in Class 12 Biology syllabus. In this topic, students learn about how new individuals are produced, the male and female reproductive systems, and how fertilization takes place in humans. This chapter helps students understand the biological process that continues life on our planet. Practicing CBSE Class 12 MCQs of Biology Chapter 3 – Human Reproduction helps students prepare better for exams like NEET Exam and CBSE Class 12 board.

The human reproduction class 12 mcq questions are framed from important NCERT Solutions topics like gametogenesis, menstrual cycle, pregnancy, and reproductive health. You can also download human reproduction class 12 mcq pdf and human reproduction class 12 ncert mcq for quick revision. Solving human reproduction class 12 mcq with answers gives you confidence and clear concept understanding.

These mcq on human reproduction class 12 are based on NCERT Solutions for Class 12 Biology, which are best for exam reference. Students should try to attempt each question with logical thinking rather than just memorizing.

CBSE Class 12 MCQs Question with Answers of Biology Chapter 3 – Human Reproduction

Ques: Humans are best described as:

a) Asexual and oviparous

b) Sexual and oviparous

c) Sexual and viviparous

d) Asexual and viviparous

Ans: c) Sexual and viviparous

Ques: Site of spermatogenesis in testis:

a) Rete testis

b) Seminiferous tubules

c) Epididymis

d) Vas deferens

Ans: b) Seminiferous tubules

Ques: Cells that secrete testosterone:

a) Sertoli cells

b) Leydig cells

c) Spermatogonia

d) Spermatids

Ans: b) Leydig cells

Ques: The structure that stores and matures sperm:

a) Epididymis

b) Prostate

c) Bulbourethral gland

d) Seminal vesicle

Ans: a) Epididymis

Ques: Major contributor to seminal fluid volume:

a) Prostate

b) Testis

c) Seminal vesicle

d) Bulbourethral gland

Ans: c) Seminal vesicle

Ques: Acrosome is derived from:

a) Golgi apparatus

b) Mitochondria

c) ER

d) Lysosome

Ans: a) Golgi apparatus

Ques: Ovulation in a typical cycle is induced by:

a) FSH surge

b) LH surge

c) Progesterone rise

d) Inhibin peak

Ans: b) LH surge

Ques: Ovulation usually occurs around day:

a) 7

b) 10

c) 14

d) 21

Ans: c) 14

Ques: The steroid critical for endometrial maintenance post‑ovulation:

a) Estradiol

b) Testosterone

c) Progesterone

d) Cortisol

Ans: c) Progesterone

Ques: Degeneration of corpus luteum without fertilisation leads to:

a) Implantation

b) Menstruation

c) Ovulation

d) Lactation

Ans: b) Menstruation

Ques: Fertilisation in humans occurs in the:

a) Uterus

b) Vagina

c) Ampulla of oviduct

d) Cervix

Ans: c) Ampulla of oviduct

Ques: Fertilisation is:

a) External

b) Internal

c) Parthenogenetic

d) Monogamous

Ans: b) Internal

Ques: The zygote divides mitotically to form a:

a) Gastrula

b) Morula then blastocyst

c) Larva

d) Trophozoite

Ans: b) Morula then blastocyst

Ques: The hormone inhibiting FSH during male gametogenesis is mainly:

a) Inhibin

b) GnRH

c) Prolactin

d) Oxytocin

Ans: a) Inhibin

Ques: The luteal phase is characterised by high:

a) FSH only

b) LH only

c) Progesterone

d) Estrogen only

Ans: c) Progesterone

Ques: Implantation is the attachment of:

a) Zygote to cervix

b) Morula to oviduct

c) Blastocyst to endometrium

d) Embryo to placenta

Ans: c) Blastocyst to endometrium

Ques: Human gestation period is approximately:

a) 28 weeks

b) 32 weeks

c) 36 weeks

d) 40 weeks

Ans: d) 40 weeks

Ques: The foeto‑maternal connection is the:

a) Amnion

b) Chorion

c) Placenta

d) Allantois

Ans: c) Placenta

Ques: The hormone that prepares mammary glands for lactation:

a) Oxytocin

b) Prolactin

c) Relaxin

d) hCG

Ans: b) Prolactin

Ques: Milk ejection (let‑down) is stimulated primarily by:

a) Progesterone

b) LH

c) FSH

d) Oxytocin

Ans: d) Oxytocin

Ques: The scrotum's key role is to:

a) Increase testicular temperature

b) Maintain lower temperature for spermatogenesis

c) Secrete sperm

d) Store sperm

Ans: b) Maintain lower temperature for spermatogenesis

Ques: Mature ovarian follicle just before ovulation:

a) Primary follicle

b) Secondary follicle

c) Tertiary follicle

d) Graafian follicle

Ans: d) Graafian follicle

Ques: Corpus luteum forms from:

a) Oocyte

b) Remaining follicular cells post‑ovulation

c) Endometrium

d) Zona pellucida

Ans: b) Remaining follicular cells post‑ovulation

Ques: Capacitation refers to:

a) Sperm maturation in epididymis

b) Acrosome formation in testis

c) Functional changes in sperm within female tract enabling fertilisation

d) Zygote cleavage

Ans: c) Functional changes in sperm within female tract enabling fertilisation

Ques: Human oogenesis produces per primary oocyte:

a) Four ova

b) Two ova

c) One ovum + polar bodies

d) Four polar bodies

Ans: c) One ovum + polar bodies

Ques: The follicular phase is dominated by:

a) Progesterone

b) Estrogen

c) hCG

d) Oxytocin

Ans: b) Estrogen

Ques: hCG is primarily secreted by:

a) Corpus luteum

b) Anterior pituitary

c) Trophoblast of embryo

d) Ovary stroma

Ans: c) Trophoblast of embryo

Ques: Chorionic villi are part of the:

a) Embryonic contribution to placenta

b) Maternal endometrium

c) Amniotic membrane only

d) Yolk sac

Ans: a) Embryonic contribution to placenta

Ques: During pregnancy, menstrual cycles stop because:

a) FSH is high

b) LH is high

c) Progesterone maintains endometrium

d) Estrogen falls drastically

Ans: c) Progesterone maintains endometrium

Ques: The event sequence in human reproduction is correctly ordered as:

a) Insemination → Gametogenesis → Fertilisation → Gestation → Parturition

b) Gametogenesis → Insemination → Fertilisation → Implantation → Gestation → Parturition

c) Fertilisation → Implantation → Gametogenesis → Insemination

d) Implantation → Fertilisation → Parturition → Gestation

Ans: b) Gametogenesis → Insemination → Fertilisation → Implantation → Gestation → Parturition

Ques: The acrosomal enzyme primarily helps in:

a) Zona pellucida penetration

b) Cleavage

c) Implantation

d) Placental circulation

Ans: a) Zona pellucida penetration

Ques: Primary spermatocyte is:

a) Haploid

b) Diploid

c) Triploid

d) Polyploid

Ans: b) Diploid

Ques: Secondary oocyte at ovulation is arrested at:

a) Prophase I

b) Metaphase II

c) Anaphase I

d) Telophase II

Ans: b) Metaphase II

Ques: The female structure homologous to male penis in erectile tissue function:

a) Labia majora

b) Labia minora

c) Clitoris

d) Cervix

Ans: c) Clitoris

Ques: Typical site of implantation in humans:

a) Cervical canal

b) Fundus/body of uterus endometrium

c) Ampulla

d) Vagina

Ans: b) Fundus/body of uterus endometrium

Ques: Which pituitary hormones regulate ovarian cycle?

a) TSH and ACTH

b) LH and FSH

c) GH and MSH

d) PRL and ADH

Ans: b) LH and FSH

Ques: The luteal phase ends if:

a) Estrogen stays high

b) hCG supports corpus luteum

c) Fertilisation does not occur and corpus luteum regresses

d) Oxytocin rises

Ans: c) Fertilisation does not occur and corpus luteum regresses

Ques: Parturition is initiated through a:

a) Purely maternal reflex

b) Neuroendocrine mechanism involving foetal signals and oxytocin

c) Mechanical rupture only

d) Decline of oxytocin

Ans: b) Neuroendocrine mechanism involving foetal signals and oxytocin

Ques: Colostrum is rich in:

a) IgA and nutrients for neonatal immunity

b) Only fats

c) Only water

d) Only RBCs

Ans: a) IgA and nutrients for neonatal immunity

Ques: Correct pairing of duct segments in male tract:

a) Seminiferous tubules → Rete testis → Vasa efferentia → Epididymis → Vas deferens → Ejaculatory duct → Urethra

b) Seminiferous tubules → Epididymis → Rete testis → Vasa efferentia → Urethra

c) Rete testis → Seminiferous tubules → Epididymis → Urethra

d) Seminiferous tubules → Vasa efferentia → Rete testis → Urethra

Ans: a) Seminiferous tubules → Rete testis → Vasa efferentia → Epididymis → Vas deferens → Ejaculatory duct → Urethra

Ques: Where does fertilisation normally occur in human females?

A) Uterus

B) Cervix

C) Vagina

D) Fallopian tube

Ans: D) Fallopian tube

Ques: Which hormone triggers ovulation?

A) FSH

B) Estrogen

C) LH

D) Progesterone

Ans: C) LH

Ques: The process of formation of sperm is called:

A) Oogenesis

B) Spermatogenesis

C) Capacitation

D) Implantation

Ans: B) Spermatogenesis

Ques: The cavity inside the blastula is known as:

A) Blastocoel

B) Archenteron

C) Coelom

D) Homocoel

Ans: A) Blastocoel

Ques: Which cell type in the testis synthesises testosterone?

A) Germ cells

B) Sertoli cells

C) Leydig cells

D) Spermatids

Ans: C) Leydig cells

Ques: The outermost layer of the uterus is called:

A) Endometrium

B) Myometrium

C) Perimetrium

D) Epimetrium

Ans: C) Perimetrium

Ques: After ovulation, the Graafian follicle transforms into:

A) Corpus atreticum

B) Corpus luteum

C) Corpus albicans

D) Corpus callosum

Ans: B) Corpus luteum

Ques: The process by which sperm gain the ability to fertilise the ovum is:

A) Spermiation

B) Capacitation

C) Fertilisation

D) Implantation

Ans: B) Capacitation

Ques: Which hormone is essential to maintain the endometrium and pregnancy?

A) FSH

B) Estrogen

C) Progesterone

D) LH

Ans: C) Progesterone

Ques: The first menstrual cycle at puberty is called:

A) Menopause

B) Menarche

C) Menses

D) Ovulation

Ans: B) Menarche

Ques: Which layer of the uterus is shed during menstruation?

A) Myometrium

B) Endometrium

C) Perimetrium

D) Epimetrium

Ans: B) Endometrium

Ques: Which of the following is a duct, not an accessory gland?

A) Seminal vesicle

B) Vas deferens

C) Prostate

D) Bulbourethral gland

Ans: B) Vas deferens

Ques: The functional unit of the human testis is:

A) Seminiferous tubule

B) Rete testis

C) Epididymis

D) Vas deferens

Ans: A) Seminiferous tubule

Ques: The membranous cover of the ovum immediately after ovulation is called:

A) Corona radiata

B) Zona pellucida

C) Chorion

D) Vitelline membrane

Ans: A) Corona radiata

Ques: Which part of sperm contains enzymes to penetrate the ovum?

A) Tail

B) Midpiece

C) Head

D) Acrosome

Ans: D) Acrosome

Ques: Normal human gestation period lasts about:

A) 7 months

B) 8 months

C) 9 months

D) 10 months

Ans: C) 9 months

Ques: Which hormone is detected in urine to confirm early pregnancy?

A) LH

B) hCG

C) Prolactin

D) Progesterone

Ans: B) hCG

Ques: Testes are maintained about how much below body temperature?

A) 1°C

B) 2°C

C) 3°C

D) 4°C

Ans: B) 2°C

Ques: The finger-like projections at the end of the oviduct are:

A) Fimbriae

B) Ampulla

C) Isthmus

D) Infundibulum

Ans: A) Fimbriae

Ques: Sequence of sperm transport: Testis → ____ → Vas deferens → Urethra.

A) Ejaculatory duct

B) Epididymis

C) Seminal vesicle

D) Prostate

Ans: B) Epididymis

Ques: Which hormone acts on Sertoli cells to regulate spermatogenesis?

A) LH

B) FSH

C) GH

D) Prolactin

Ans: B) FSH

Ques: The stage between zygote and blastocyst is:

A) Gastrula

B) Morula

C) Embryo

D) Fetus

Ans: B) Morula

Ques: Viability of human ovum for fertilisation after ovulation is about:

A) 1–2 hours

B) 12–24 hours

C) 2 days

D) 3 days

Ans: B) 12–24 hours

Ques: Which structure is NOT part of female accessory ducts?

A) Uterus

B) Oviduct

C) Vagina

D) Ovary

Ans: D) Ovary

Ques: Reaction that prevents polyspermy in the ovum is:

A) Acrosomal reaction

B) Cortical reaction

C) Bindin reaction

D) Acrosin reaction

Ans: B) Cortical reaction

Ques: Which of these is NOT secreted by the human placenta?

A) hCG

B) Progesterone

C) Estrogen

D) LH

Ans: D) LH

Ques: In human females, menopause typically occurs around:

A) 40 years

B) 50 years

C) 60 years

D) 70 years

Ans: B) 50 years

Ques: The release of a mature ovum from the ovary is:

A) Implantation

B) Ovulation

C) Menstruation

D) Fertilisation

Ans: B) Ovulation

Ques: The part of the sperm rich in mitochondria is the:

A) Head

B) Acrosome

C) Midpiece

D) Tail

Ans: C) Midpiece

Ques: Spermiation refers to:

A) Release of sperms from seminiferous tubules

B) Capacitation in female tract

C) Fertilisation

D) Implantation

Ans: A) Release of sperms from seminiferous tubules

Ques: During the menstrual cycle, endometrium regenerates approximately during:

A) Days 1–4

B) Days 5–10

C) Days 11–17

D) Days 18–23

Ans: B) Days 5–10